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TdT-IN-1

CAT: 0804-HY-174849Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-174849Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TdT-IN-1 (Compound 8c) is a selective and non-nucleoside terminal deoxynucleotidyl transferase (TdT) inhibitor with IC50 s of 0.11 and 0.19 μM for Mg2+ and Mn2+. TdT-IN-1 can be used for leukaemias and skin cancer research[1].
UNSPSC
12352005
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=C(O)/C(O)=C/C(/C=C/C1=CNC=C1C2=CC=CC=C2)=O
Molecular Formula
C16H13NO4
Molecular Weight
283.28
References & Citations
[1]Madia VN, et al. Exploring structure-activity relationships of pyrrolyl diketo acid derivatives as non-nucleoside inhibitors of terminal deoxynucleotidyl transferase enzyme. J Enzyme Inhib Med Chem. 2025 Dec;40 (1) :2496782.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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