Adrenosterone (Standard)

• Description :

  Adrenosterone (Standard) is the analytical standard of Adrenosterone. This product is intended for research and analytical applications. Adrenosterone ((+) -Adrenosterone) is a competitive hydroxysteroid (11-beta) dehydrogenase 1 (HSD11β1) inhibitor. Adrenosterone is a steroid hormone with weak androgenic effect. Adrenosterone is a dietary supplement that can decrease fat and increase muscle mass. Adrenosterone acts as a suppressor of metastatic progression of human cancer cells[1][2][3].

• UNSPSC :

  12352100

• Target :

  Androgen Receptor; Endogenous Metabolite; Reference Standards

• Related Pathways :

  Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor

• Field of Research :

  Cancer; Endocrinology

• Purity :

  98.58

• Smiles :

  C[C@@]([C@](CC1)([H])[C@]2([H])CCC3=CC(CC[C@]3(C)[C@@]2([H])C4=O)=O)(C4)C1=O

• Molecular Formula :

  C19H24O3

• Molecular Weight :

  300.39

• References & Citations :

  [1]Brooker L, et al. Carbon isotope ratio analysis of endogenous glucocorticoid urinary metabolites after cortisone acetate andadrenosterone administration for doping control. Drug Test Anal. 2012 Dec;4 (12) :951-61.|[2]Choudhary MI, et al. Biotransformation of adrenosterone by filamentous fungus, Cunninghamella elegans. Steroids. 2007 Dec;72 (14) :923-9.|[3]Joji Nakayama, et al. A Novel Zebrafish Model of Metastasis Identifies the HSD11β1 Inhibitor Adrenosterone as a Suppressor of Epithelial-Mesenchymal Transition and Metastatic Dissemination. Mol Cancer Res. 2020 Mar;18 (3) :477-487.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, sealed storage, away from light and moisture

• Scientific Category :

  Reference Standards

• CAS Number :

  [382-45-6]