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NM600

CAT: 0804-HY-174418Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-174418Size:1 Each
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Description
NM600 is an alkylphosphocholine mimetic RPT agent. NM600 demonstrates an antitumor activity against a second GD2+ neuroblastoma xenograft model with SY5Y cells. NM600 can enhance suboptimal CAR T cell efficacy against solid tumors. NM600 can be studied in research for neuroblastoma[1].
CAS Number
2097522-37-5
UNSPSC
12352128
Target
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Smiles
O=P(OCC[N+](C)(C)C)([O-])OCCCCCCCCCCCCCCCCCCC1=CC=C(NC(CN2CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC2)=O)C=C1
Molecular Formula
C45H81N6O11P
Molecular Weight
913.13
References & Citations
[1] Sodji QH, et al., Low-dose radiation by radiopharmaceutical therapy enhances GD2 TRAC-CAR T cell efficacy in localized neuroblastoma. Sci Adv. 2025 Jun 6;11 (23) :eadu4417.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

2-(Trimethylazaniumyl)ethyl 18-[4-[[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetyl]amino]phenyl]octadecyl phosphate
CAS Number2097522-37-5
PubChem CID134194848
IUPAC Name2-(trimethylazaniumyl)ethyl 18-[4-[[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetyl]amino]phenyl]octadecyl phosphate
Molecular FormulaC45H81N6O11P
Molecular Weight913.1
XLogP0.3
Topological Polar Surface Area213
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count15
Rotatable Bond Count33
Heavy Atom Count63
Formal Charge0
Complexity1280
SMILES
C[N+](C)(C)CCOP(=O)([O-])OCCCCCCCCCCCCCCCCCCC1=CC=C(C=C1)NC(=O)CN2CCN(CCN(CCN(CC2)CC(=O)O)CC(=O)O)CC(=O)O
InChI
InChI=1S/C45H81N6O11P/c1-51(2,3)33-35-62-63(59,60)61-34-19-17-15-13-11-9-7-5-4-6-8-10-12-14-16-18-20-40-21-23-41(24-22-40)46-42(52)36-47-25-27-48(37-43(53)54)29-31-50(39-45(57)58)32-30-49(28-26-47)38-44(55)56/h21-24H,4-20,25-39H2,1-3H3,(H4-,46,52,53,54,55,56,57,58,59,60)
InChIKey
MCBYYGYMPQYUDB-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2-(Trimethylazaniumyl)ethyl 18-[4-[[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetyl]amino]phenyl]octadecyl phosphate
CAS: 2097522-37-5
CID: 134194848
Formula: C45H81N6O11P
MW: 913.1
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight913.1
XLogP30.3
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count15
Rotatable Bond Count33
Exact Mass912.57009442
Monoisotopic Mass912.57009442
Topological Polar Surface Area213 Ų
Heavy Atom Count63
Formal Charge0
Complexity1280
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
T211187-01NM600

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