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Antifungal agent 134

CAT: 0804-HY-174388Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-174388Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Antifungal agent 134 (Compound B13) is an antifungal agent with EC50s of 3.24, 1.89, 1.70, 0.36, 4.27, and 1.50 μg/mL for Botrytis cinerea, Alternaria solani, Fusarium graminearum, Rhizoctonia solani, Colletotrichum orbiculare, and Alternaria alternata, respectively. Antifungal agent 134 can disrupt the cell membrane and mitochondria of the hyphae, leading to significant ROS accumulation. Antifungal agent 134 also has significant herbicidal activities against field weeds, such as Amaranthus retroflexus L and Abutilon theophrasti Medicus. Antifungal agent 134 can be used for crop diseases and field weeds research[1].
CAS Number
3080992-04-4
UNSPSC
12352005
Target
Fungal; Herbicide; Reactive Oxygen Species (ROS)
Related Pathways
Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Infection
Smiles
O=C(NNC1=CC=C(F)C=C1)COC2=CC(O3)=C(C=C2)C(C(F)(F)F)=CC3=O
Molecular Formula
C18H12F4N2O4
Molecular Weight
396.29
References & Citations
[1]Li Y, et al. Discovery of Coumarin-7-N/O-Acethydrazide Derivatives as Novel Antifungal and Herbicidal Agents. J Agric Food Chem. 2025 Jun 18;73 (24) :14783-14795.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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