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Rabbit Polyclonal Antibody to RPC8 (N-term)

CAT: 1725-P30608-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P30608-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RPC8 is DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. It is plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. It is acting as nuclear and cytosolic DNA sensor involved in innate immune response. It can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway.
Product Name Alternative
DNA-directed RNA polymerase III subunit RPC8, RNA polymerase III subunit C8, DNA-directed RNA polymerase III subunit H, RNA polymerase III subunit 229 kDa subunit, RPC229, POLR3H, KIAA1665, RPC8
Swiss Prot
Q9Y535
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This RPC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5-33 amino acids from the N-terminal region of human RPC8.
Clonality
Polyclonal
Applications
WB, FCM
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide.
Antibody Type
Primary antibody
Protein Name
RPC8 (N-term)
Bands Size
22.9kDa

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