BRCA2-IN-1

• Description :

  BRCA2-IN-1 (Compound 3j) is a potential BRCA2 inhibitor that exhibits antiproliferative activity against the breast cancer MCF-7 cell lines. BRCA2-IN-1 also demonstrates DPPH radical scavenging ability, with an IC50 of 12.36 µM[1].

• UNSPSC :

  12352005

• Target :

  Reactive Oxygen Species (ROS)

• Related Pathways :

  Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Field of Research :

  Cancer

• Smiles :

  O=S(C1=CC=C(/N=N/C2=CC=C(O)C(/C=N/NC(N)=S)=C2)C=C1)(N)=O

• Molecular Formula :

  C14H14N6O3S2

• Molecular Weight :

  378.43

• References & Citations :

  [1]Rezaeianzadeh O, et, al. Synthesis and application of diazenyl sulfonamide-based schiff bases as potential BRCA2 active inhibitors against MCF-7 breast cancer cell line. Sci Rep. 2025 Feb 24;15 (1) :6661.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported