BRCA2-RAD51-IN-1
CAT:
804-HY-162104
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
BRCA2-RAD51-IN-1
- CAS Number: 2830213-53-9
- UNSPSC Description: BRCA2-RAD51-IN-1 (Compound 46) is a BRCA2-RAD51 inhibitor with an EC50 value of 28 μM. BRCA2-RAD51-IN-1 has antitumor activity[1].
- Target Antigen: Others
- Type: Reference compound
- Related Pathways: Others
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/brca2-rad51-in-1.html
- Solubility: 10 mM in DMSO
- Smiles: BrC1=CC=CC(C(NC2=CC(C(F)(F)F)=NN23)=CC3=O)=C1
- Molecular Weight: 358.11
- References & Citations: [1]Myers SH, et al. An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer. Eur J Med Chem. 2023 Dec 31;265:116114.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported