HBV-IN-51

CAT: 0804-HY-173120Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-173120Size:1 Each

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Description

HBV-IN-51 (Compound 17e) is a potent HBV capsid assembly modulator. HBV-IN-51 exhibits remarkable anti-HBV activity with an EC50 of 0.033 μM in HepAD38 cells. HBV-IN-51 exhibits robust metabolic stability in plasma, and can be rapidly metabolized in human liver microsomes[1].

UNSPSC

12352005

Target

HBV

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

S=C(N(C)C(C)C)NC1=CC(C(NC2=CC(F)=C(F)C(F)=C2)=O)=C(C3CC3)C=C1F

Molecular Formula

C21H21F4N3OS

Molecular Weight

439.47

References & Citations

[1]Wang M, et, al. Design and biochemical evaluation of 2-cyclopropyl-thioureidobenzamide (CP-TBA) derivatives as potent HBV capsid assembly modulators targeting a novel binding site. Eur J Med Chem. 2025 May 5:289:117441.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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