IDB-001

• Description :

  IDB-001 is an inhibitor of ribosome PTC that inhibits protein synthesis in a sequence-selective manner. IDB-001 inhibits HCC-1143 with a EC50 value of 0.84 μM. IDB-001 inhibits MYC-dependent cancer cell viability[1].

• UNSPSC :

  12352211

• Target :

  DNA/RNA Synthesis

• Related Pathways :

  Cell Cycle/DNA Damage

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Concentration :

  10mM

• Purity :

  99.48

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  O=C(NCC[C@@H]1CCCN1)O[C@H]([C@H](CN2)O)[C@H]2CC3=CC=C(C=C3)OC

• Molecular Formula :

  C19H29N3O4

• Molecular Weight :

  363.45

• References & Citations :

  [1]Paige D. Diamond, et al. Context-dependent translation inhibition as a novel oncology therapeutic modality. bioRxiv. January 09, 2025.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light, stored under nitrogen)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [3079913-81-5]