HCy-Lyso

• Description:

  HCy-Lyso is a lysosome-targeting turn-on fluorescent probe based on hydrocyanine. HCy-Lyso integrates a hydrocyanine moiety for selective recognition of hydroxyl radicals (•OH) and a morpholine group for lysosome targeting. Upon reacting with •OH, HCy-Lyso undergoes an extension of its π-conjugation system, producing a strong fluorescence signal at 598 nm when excited at 510 nm[1][2].

• UNSPSC:

  12171500

• Target:

  Fluorescent Dye

• Related Pathways:

  Others

• Field of Research:

  Others

• Smiles:

  CC1 (C (N (C2=CC=CC=C12) CC) /C=C/C3=CC=C (N4CCOCC4) C=C3) C

• Molecular Formula:

  C24H30N2O

• Molecular Weight:

  362.51

• References & Citations:

  [1]Ransdell-Green EC, et al. Advances in Fluorescence Techniques for the Detection of Hydroxyl Radicals near DNA and Within Organelles and Membranes. Antioxidants (Basel) . 2025 Jan 10;14 (1) :79. |[2]Zhong L, et al. Rational design of a lysosome-targeted fluorescent probe for monitoring the generation of hydroxyl radicals in ferroptosis pathways. RSC Adv. 2024 Apr 22;14 (18) :12864-12872.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Dye Reagents

• Clinical Information:

  No Development Reported