HCy-Lyso

• Description :

  HCy-Lyso is a lysosome-targeting turn-on fluorescent probe based on hydrocyanine. HCy-Lyso integrates a hydrocyanine moiety for selective recognition of hydroxyl radicals (•OH) and a morpholine group for lysosome targeting. Upon reacting with •OH, HCy-Lyso undergoes an extension of its π-conjugation system, producing a strong fluorescence signal at 598 nm when excited at 510 nm[1][2].

• UNSPSC :

  12171500

• Target :

  Fluorescent Dye

• Related Pathways :

  Others

• Field of Research :

  Others

• Smiles :

  CC1(C(N(C2=CC=CC=C12)CC)/C=C/C3=CC=C(N4CCOCC4)C=C3)C

• Molecular Formula :

  C24H30N2O

• Molecular Weight :

  362.51

• References & Citations :

  [1]Ransdell-Green EC, et al. Advances in Fluorescence Techniques for the Detection of Hydroxyl Radicals near DNA and Within Organelles and Membranes. Antioxidants (Basel) . 2025 Jan 10;14 (1) :79. |[2]Zhong L, et al. Rational design of a lysosome-targeted fluorescent probe for monitoring the generation of hydroxyl radicals in ferroptosis pathways. RSC Adv. 2024 Apr 22;14 (18) :12864-12872.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Dye Reagents

• Clinical Information :

  No Development Reported