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(3S,6R) -NML

CAT: 0804-HY-172213Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-172213Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(3S,6R) -NML is a NMDA receptor antagonist, with pIC50s of 4.8 (GluN1-GluN2A), 4.6 (GluN1-GluN2B), 5.0 (GluN1-GluN2C), 5.0 (GluN1-GluN2D) respectively. (3S,6R) -NML can be used for depression research[1].
CAS Number
1585965-04-3
UNSPSC
12352005
Target
IGluR
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
CC[C@H](O)C(C1=CC=CC=C1)(C2=CC=CC=C2)C[C@H](NC)C
Molecular Formula
C20H27NO
Molecular Weight
297.43
References & Citations
[1]Banzato M, et al. New Synthesis and Pharmacological Evaluation of Enantiomerically Pure (R) - and (S) -Methadone Metabolites as N-Methyl-d-aspartate Receptor Antagonists. J Med Chem. 2025 Feb 25.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NMDA Receptor

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