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POPTc80-IN-1

CAT: 0804-HY-172207Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-172207Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
POPTc80-IN-1 (Compound LC-45) is a competitive inhibitor for prolyl oligopeptidase of Trypanosoma cruzi POPTc80 with an IC50 of 0.23 μM and a Ki of 0.054 μM. POPTc80-IN-1 inhibits the invasion of T. cruzi into host cell with an IC50 of 46.71 μM[1].
UNSPSC
12352005
Target
Parasite; Ser/Thr Protease
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
O=C(C1C(C(N2CCCC2)=O)CCCC1)NCCC3=CSC=N3
Molecular Formula
C17H25N3O2S
Molecular Weight
335.46
References & Citations
[1]Costa VAF, et al., Structure-Based Identification of Non-covalent Prolyl Oligopeptidase 80 Inhibitors Targeting Trypanosoma cruzi Cell Entry. J Chem Inf Model. 2025 Mar 10;65 (5) :2636-2649.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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