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Anti-NASH agent 2

CAT: 0804-HY-172105Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-172105Size:1 Each
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Description
Anti-NASH agent 2 (compound 21) is an inhibitor of de novo adipogenesis activity and α-SMA gene expression. Anti-NASH agent 2 improves hepatic steatosis, edema, inflammatory infiltrates, and liver fibrosis in NASH mouse models[1].
CAS Number
3028778-28-8
UNSPSC
12352005
Target
PPAR
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease; Inflammation/Immunology
Smiles
[H][C@@]12[C@@H](O)CC3=C([C@H](C)CCN4C=C(CC(C)C)N=N4)CC[C@]3(C)[C@@]1(C)CC[C@@]5([H])C(C(CC[C@]25C)=O)(C)C
Molecular Formula
C32H51N3O2
Molecular Weight
509.77
References & Citations
[1]Yu NR, et al. Design, synthesis and biological evaluation of Alisol B derivatives for potential treatment of non-alcoholic steatohepatitis. Bioorg Chem. 2025 Jan 7;155:108132.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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