EGFR-IN-145

CAT: 0804-HY-171252-01Size: 1 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-171252-01Size:1 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

EGFR-IN-145 (compound 7c) is an EGFR kinase inhibitor. At a concentration of 20 μM, EGFR-IN-145 has an inhibition rate of 52.7% on EGFR-wild type kinase[1].

CAS Number

852407-49-9

UNSPSC

12352005

Target

EGFR

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Smiles

FC(C=C1)=CC=C1CNC2=C3C(SC4=C3CCCC4)=NC=N2

Molecular Formula

C17H16FN3S

Molecular Weight

313.39

References & Citations

[1]Wu CH, et al. Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and Michael acceptor group for maximal potency. J Med Chem. 2010 Oct 28;53 (20) :7316-26.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Related Products

Catalog	Name
HY-P10345	OP-145
HY-107536-01	ML 145
HY-162348	Antitumor agent-145
HY-149353	Antibacterial agent 145
HY-143340	LEB-03-145
HY-RI00281-01	Hsa-miR-145-3p inhibitor
HY-RI04235-01	Rno-miR-145-3p inhibitor
HY-R00282A-01	Hsa-miR-145-5p agomir
HY-RI00282-01	Hsa-miR-145-5p inhibitor
HY-R00281-01	Hsa-miR-145-3p mimic

Alternative Products

Catalog	Name
T204326-01	EGFR-IN-145
T70541-01	IS-145
CL-0566	MARC-145 [Marc-145; Marc 145; Marc145] Cell Line
FP43074-01	IPI 145
2445-5	IPI-145
MBS3844405-01	ML 145
ABC-TC0003	145-2C11
C0019004	DU 145
sc-65759	AChRγ (145)
TRC-J211535-100MG	JWH-145

EGFR-IN-145

Related Products

Alternative Products

Popular Products