(S) -YNT-3708

• Description:

  (S) -YNT-3708, the S-enantiomer of YNT-3708, with low activity for OX1R and OX2R (EC50 = 3595 nM and 1661 nm, respectively) [1].

• UNSPSC:

  12352005

• Target:

  Orexin Receptor (OX Receptor)

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Purity:

  99.80

• Solubility:

  DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  O=C(N(C)[C@H]1CCCC2=C1C=C(NS(=O)(C3=CC(/C=C/C(NC4=CC=NC=C4)=O)=CC=C3OC)=O)C=C2)CC5=CC=CC(OC)=C5

• Molecular Formula:

  C35H36N4O6S

• Molecular Weight:

  640.75

• References & Citations:

  [1]Keita Iio, et al. Design and Synthesis of Orexin 1 Receptor-Selective Agonists. J Med Chem. 2023 Apr 27;66 (8) :5453-5464.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2923138-00-3