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YNT-185

CAT: 0931-T39229-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T39229-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1804978-81-1
Target
OX Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Purity
0.9967
Bioactivity
YNT-185 is a nonpeptide, selective agonist of the orexin type-2 receptor (OX2R), with EC50 values of 0.028 μM for OX2R and 2.75 μM for OX1R. Additionally, YNT-185 effectively alleviates symptoms of narcolepsy-cataplexy in mouse models.
Smiles
S(NC1=CC(NCCNC(=O)C2=C(N(C)C)C=CC=C2)=CC=C1)(=O)(=O)C3=C(OC)C=CC(=C3)C4=CC(C(N(C)C)=O)=CC=C4
Molecular Formula
C33H37N5O5S
Molecular Weight
615.74
Shipping Conditions
Ice Packs
Storage Temperature
-20°C