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C12-rrw-NH2

CAT: 0804-HY-170991Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-170991Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
C12-rrw-NH2 (Compound Lip7) is an antibacterial agent against gram-positive bacteria, especially against Methicillin -resistant Staphylococcus aureus (MRSA). C12-rrw-NH2 induces bacterial death via depolarizing the bacterial cytoplasmic membrane, disrupting the integrity of the bacterial membrane, leading to leakage of nucleic acid and protein and promoting the generation of Reactive Oxygen Species. C12-rrw-NH2 is potential to be used for research of developing high-stability antimicrobial peptides[1].
UNSPSC
12352005
Target
Bacterial; Reactive Oxygen Species (ROS)
Related Pathways
Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Infection
Smiles
CCCCCCCCCCCC(N[C@H](CCCNC(N)=N)C(N[C@H](CCCNC(N)=N)C(N[C@H](CC1=CNC2=C1C=CC=C2)C(O)=O)=O)=O)=O
Molecular Formula
C35H58N10O5
Molecular Weight
698.90
References & Citations
[1]Zou J, et al. Ultra-short lipopeptides containing d-amino acid exhibiting excellent stability and antibacterial activity against gram-positive bacteria. Eur J Med Chem. 2025 Apr 5;287:117341.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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