Hypoglycemic agent 3

• Description :

  Hypoglycemic agent 3 (Compound H26), a derivative of corosolic acid, exhibits lipid-lowering and significant hypoglycemic effects and can be used as a hypoglycemic agent. Hypoglycemic agent 3 inhibits insulin resistance by targeting MCCC1 and can be used in the study of type 2 diabetes[1].

• UNSPSC :

  12352211

• Target :

  Akt; NF-κB; PI3K

• Related Pathways :

  NF-κB; PI3K/Akt/mTOR

• Field of Research :

  Metabolic Disease

• Smiles :

  O=C(O)CNC([C@]12CC[C@@H](C)[C@H](C)[C@@]1([H])C3=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)C(C)(C)C5CC[C@@]4(C)[C@]3(C)CC2)=O

• Molecular Formula :

  C32H51NO5

• Molecular Weight :

  529.75

• References & Citations :

  [1]Huang G, et al. Corosolic acid and its derivatives targeting MCCC1 against insulin resistance and their hypoglycemic effect on type 2 diabetic mice[J]. European Journal of Medicinal Chemistry, 2024: 117184.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported