Products for Research Use Only
RegisterLogin

DALK-3

CAT: 0804-HY-170592Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-170592Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
DALK-3 is an anaplastic lymphoma kinase (ALK) degrader. dALK-3 can effectively induce EML4-ALK degradation with a DC50 of 0.182 μM. dALK-3 has good anti-proliferation activity against H3122 cells and can be used in the study of cancer[1].
UNSPSC
12352005
Target
Anaplastic lymphoma kinase (ALK)
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
ClC1=C(NC2=CC=CC=C2P(C)(C)=O)N=C(NC3=C(OC)C=C(N4CCC(N5CCN(C(/C=C/C(C6=CC=C(OC)C=C6)=O)=O)CC5)CC4)C=C3)N=C1
Molecular Formula
C39H45ClN7O5P
Molecular Weight
758.25
References & Citations
[1]Yu N, et al. Design and evaluation of anaplastic lymphoma kinase degraders using a covalent fumarate handle. Bioorg Med Chem Lett. 2024 Dec 15;117:130075.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-151508Diamino lipid DAL4
HY-W081226-013,3,3-Trifluoropropionyl chloride
HY-W127810-013,3',3''-Nitrilotripropionic Acid
HY-W4403031,1',3,3,3',3'-Hexamethylindotricarbocyanine (perchlorate)
HY-W1146693- (3- (3-Ethoxy-3-oxopropoxy) propoxy) propanoicacid
HY-D1075-011,1',3,3,3',3'-Hexamethylindodicarbocyanine (iodide)
HY-79034-013,3-Dimethylcyclohexanone
HY-131942SFTX-3.3
HY-178928KV1.3-IN-3
HY-176547FGFR2/3-IN-3

Alternative Products

CatalogName
T204519-01DALK-3
PC68253,3,3-Trifluoropropyl 3,3,3-trifluoropropanoate
QMC01729-013- (3,3,3-Trifluoropropoxy) pyridine
JFC42829-013- (3,3,3-Trifluoropropyl) aniline
sc-2604333- (3,3,3-Trifluoropropyl) heptamethyltrisiloxane
PDC53711-013- (3,3,3-Trifluoropropoxy) piperidine
NU-456L3',3',3'-cAAG
JMB17199-013,3,3-Trifluoropropanehydrazide
sc-2611293,3,3-Trifluoropropionitrile
PC4452-013,3,3-Trifluoropropylmethyldimethoxysilane

Popular Products