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JAK05

CAT: 0804-HY-170586Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-170586Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JAK05 exhibits inhibitory activity against Helicobacter pylori, inhibits strains J63, J196 and J107 with MIC of 3-5 µg/mL. JAK05 exhibits binding affinity to H+/K+-ATPase, COX-1/2, TNF-α and PGE2, reveals antioxidant and anti-inflammatory activities. JAK05 exhibits anti-ulcer activity in rat ethanol-induced gastric ulcer models[1].
UNSPSC
12352005
Target
Bacterial; COX; Na+/K+ ATPase; Prostaglandin Receptor; TNF Receptor
Related Pathways
Anti-infection; Apoptosis; GPCR/G Protein; Immunology/Inflammation; Membrane Transporter/Ion Channel
Field of Research
Infection; Inflammation/Immunology
Smiles
ClC(C=C1)=CC=C1N2C(C3=CC=NC=C3)=NN([C@H]4O[C@@H](COC(C)=O)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@@H]4OC(C)=O)C2=S
Molecular Formula
C27H27ClN4O9S
Molecular Weight
619.04
References & Citations
[1]Azam J, et al., Pharmacological investigation of selected 1,2,4 triazole derivative against ethanol induced gastric ulcer. Bioorg Chem. 2025 Jan;154:108040.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
T204688-01JAK05

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