JAK05

CAT: 0931-T204688-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T204688-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

Antibacterial, TNF, Prostaglandin Receptor, ATPase, COX

Related Pathways

Immunology/Inflammation, Microbiology/Virology, Apoptosis, Neuroscience, GPCR/G Protein, Membrane transporter/Ion channel

Bioactivity

JAK05 exhibits inhibitory activity against Helicobacter pylori, effectively suppressing strains J63, J196, and J107, with a MIC of 3-5 μg/mL. It shows affinity for binding to H+/K+-ATPase, COX-1/2, TNF-α, and PGE2, and possesses antioxidant and anti-inflammatory properties. In a rat model of ethanol-induced gastric ulcers, JAK05 demonstrates anti-ulcer activity.

Smiles

CC(=O)OC[C@H]1[C@@H]([C@@H]([C@@H]([C@H](O1)N2C(=S)N(C(=N2)C3=CC=NC=C3)C4=CC=C(C=C4)Cl)OC(=O)C)OC(=O)C)OC(=O)C

Molecular Formula

C27H27ClN4O9S

Molecular Weight

619.043

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
HY-170586	JAK05

JAK05

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