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Ac-EEVC-OH

CAT: 0804-HY-170534-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0804-HY-170534-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ac-EEVC-OH is the linker, that can be used for synthesis of ADC molecule[1].
CAS Number
[2921734-44-1]
UNSPSC
12352209
Target
ADC Linker
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.11
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C)(C)OC(CC[C@H](NC(C)=O)C(N[C@@H](CCC(OC(C)(C)C)=O)C(N[C@@H](C(C)C)C(N[C@H](C(O)=O)CCCNC(N)=O)=O)=O)=O)=O
Molecular Formula
C31H54N6O11
Molecular Weight
686.79
References & Citations
[1]Watanabe T, et al., Exo-Cleavable Linkers: Enhanced Stability and Therapeutic Efficacy in Antibody-Drug Conjugates. J Med Chem. 2024 Oct 24;67 (20) :18124-18138.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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