CNJ-294

• Description:

  CNJ-294 is an intermediate in the synthesis of Capmatinib (HY-13404) and a metabolite of Capmatinib (HY-13404) [1][2].

• UNSPSC:

  12352005

• Target:

  Drug Intermediate; Drug Metabolite

• Related Pathways:

  Metabolic Enzyme/Protease; Others

• Field of Research:

  Others

• Smiles:

  O=C(C1=C(F)C=C(C2=NN3C(N=C2)=NC=C3CC4=CC5=CC=CN=C5C=C4)C=C1)N

• Molecular Formula:

  C22H15FN6O

• Molecular Weight:

  398.39

• References & Citations:

  [1]Qingquan Lian. Preparation method of carbamatinib. CN111825678 A. 2020-10-27.|[2]Glaenzel U, et al. Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite. Drug Metab Dispos. 2020 Oct;48 (10) :873-885.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Oligonucleotides

• Clinical Information:

  No Development Reported

• CAS Number:

  [1029713-99-2]