AS2690168 (freebase)

• Description:

  AS2690168 freebase is an orally active RANKL signal transduction inhibitor which suppresses RANKL-induced osteoclastogenesis of RAW264 cells. AS2690168 can be utilized in research related to pathological osteolysis[1].

• UNSPSC:

  12352005

• Target:

  RANKL/RANK

• Related Pathways:

  NF-κB

• Field of Research:

  Others

• Smiles:

  FC1=CC (F) =C (CNC2=C (OC) C=NC (C3=NC=CC=C3) =N2) C (F) =C1

• Molecular Formula:

  C17H13F3N4O

• Molecular Weight:

  346.31

• References & Citations:

  [1]Morikawa N, et al. Pharmacological characterization of AS2690168, a novel small molecule RANKL signal transduction inhibitor. Eur J Pharmacol. 2022 Jun 5;924:174941.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1393999-78-4