Fluralaner-d2

• Description :

  Fluralaner-d2 (A1443-d2) is deuterium labeled Fluralaner. Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of GABA and L-glutamate gated chloride channels.

• Product Name Alternative :

  A1443-d2; AH252723-d2

• UNSPSC :

  12352005

• Target :

  Isotope-Labeled Compounds; Parasite

• Related Pathways :

  Anti-infection; Others

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Smiles :

  O=C(C1=CC=C(C=C1C)C2=NOC(C3=CC(Cl)=CC(Cl)=C3)(C2)C(F)(F)F)NCC(NC([2H])([2H])C(F)(F)F)=O

• Molecular Formula :

  C22H15D2Cl2F6N3O3

• Molecular Weight :

  558.30

• References & Citations :

  [2]Williams H, et al. Fluralaner, a novel isoxazoline, prevents flea (Ctenocephalides felis) reproduction in vitro and in asimulated home environment. Parasit Vectors. 2014 Jun 19;7:275.|[3]Walther FM, et al. Safety of fluralaner, a novel systemic antiparasitic drug, in MDR1 (-/-) Collies after oral administration. Parasit Vectors. 2014 Mar 6;7:86.|[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported