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RBx-0597

CAT: 0804-HY-169724Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-169724Size:1 Each
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Description
RBx-0597 is a potent and selective DPP-IV inhibitor, demonstrating IC50 values of 32, 31, and 39 nM against human, mouse, and rat plasma DPP-IV, respectively. RBx-0597 shows potential for type 2 diabetes research[1].
CAS Number
929105-33-9
UNSPSC
12352005
Target
Dipeptidyl Peptidase
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Smiles
O=C(N1[C@@H](C[C@@H](C1)F)C#N)CN[C@@H]2[C@]3([H])[C@@]2([H])CN(C3)C(C4=CC=C(C=C4)F)=O
Molecular Formula
C19H20F2N4O2
Molecular Weight
374.38
References & Citations
[1]Singh S, et al. RBx-0597, a potent, selective and slow-binding inhibitor of dipeptidyl peptidase-IV for the treatment of type 2 diabetes. Eur J Pharmacol. 2011 Feb 10;652 (1-3) :157-63.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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