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DBMB

CAT: 0804-HY-169630Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-169630Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DBMB is an inhibitor of spleen tyrosine kinase (Syk), capable of significantly inhibiting the activity of Syk kinase. DBMB exhibits anti-inflammatory activity by suppressing the signaling of NF-κB, which in turn reduces the production of inflammatory mediators such as nitric oxide (NO) and prostaglandin E2 (PGE2) . DBMB can be utilized in research on inflammatory diseases[1].
CAS Number
314027-66-2
UNSPSC
12352005
Target
NF-κB; NO Synthase; Prostaglandin Receptor; Syk
Related Pathways
GPCR/G Protein; Immunology/Inflammation; NF-κB; Protein Tyrosine Kinase/RTK
Field of Research
Inflammation/Immunology
Smiles
COC1=C(C=CC=C1)CC(C2=NC3=C(N2)C=CC=C3)CC4=NC5=C(N4)C=CC=C5
Molecular Formula
C24H22N4O
Molecular Weight
382.46
References & Citations
[1]Kim E, et al. 1- (2, 3-dibenzimidazol-2-ylpropyl) -2-methoxybenzene is a Syk inhibitor with anti-inflammatory properties[J]. Molecules, 2016, 21 (4) : 508.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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