NSD-IN-4

• Description:

  NSD-IN-4 (Compound A8) is a potent and an orally active NSD3 inhibitor. NSD-IN-4 induces Apoptosis in a dose-dependent manner. NSD-IN-4 exhibits significant antitumor effects against lung squamous carcinoma[1].

• UNSPSC:

  12352211

• Target:

  Apoptosis; Histone Methyltransferase

• Related Pathways:

  Apoptosis; Epigenetics

• Field of Research:

  Cancer

• Smiles:

  O=C(C(Cl)=C1NCCC2=CC=CC(F)=C2)C3=C(N=CC=C3)C1=O

• Molecular Formula:

  C17H12ClFN2O2

• Molecular Weight:

  330.74

• References & Citations:

  [1]Xiu S, et al. Design, Synthesis, and Antitumor Activity of NSDs Inhibitors Targeting Lung Squamous Cell Carcinoma. European Journal of Medicinal Chemistry, 2025: 117388.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported