BI-1942

• Description :

  BI-1942, a chemical probe, is a chymase inhibitor and has an IC50 of 0.4 nM for human chymase. BI-1942 can be used in the research of ophthalmic diseases[1].

• CAS Number :

  [1236524-95-0]

• UNSPSC :

  12352005

• Target :

  Proteasome

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Others

• Smiles :

  CN1C2=CC(C)=CC(C)=C2C(CN3C4=CC=CN=C4C(N(C3=O)[C@H](CC)CC(O)=O)=O)=C1

• Molecular Formula :

  C24H26N4O4

• Molecular Weight :

  434.49

• References & Citations :

  [1]Abbe P, et al. Metadata analysis of Boehringer Ingelheim's opnMe database reveals the potential of BI-1942, a chymase inhibitor, for ophthalmic indications repurposing. Investigative Ophthalmology & Visual Science, 2024, 65 (7) : 6126-6126.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported