TBC-1

• Description:

  TBC-1 is a chlorophyll-a derivative, is a photosensitizer that can be used in photodynamic therapy (PDT) . TBC-1 efficiently generats Type-I ROS and endoplasmic reticulum targeting ability. TBC-1 shows biocompatibility and PDT efficiency in vitro under both normoxia and hypoxia[1].

• UNSPSC:

  12352101

• Target:

  Photosensitizer; Reactive Oxygen Species (ROS)

• Related Pathways:

  Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Smiles:

  BrC1=CC=C2C(CN3C4=C(CN2C3)C=C(/C=C/C(C5=CC6=C(OC5=O)C=C(C=C6)N(CC)CC)=O)C=C4)=C1

• Molecular Formula:

  C31H28BrN3O3

• Molecular Weight:

  570.48

• References & Citations:

  [1]Rui Yuan, et al. Tröger’s Base as a Potential Bridge to Type-I Photosensitizers: Mechanism and Antitumor Applications. J Med Chem. 2025 Jan 7.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2522115-48-4]