INCB159020

CAT: 0804-HY-168847Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-168847Size:1 Each

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Description

INCB159020 is an orally active KRAS G12D inhibitor with a KRAS G12D SPR value of 2.2 nM. INCB159020 has antitumor activity[1].

CAS Number

2923669-20-7

UNSPSC

12352101

Target

Ras

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Field of Research

Cancer

Smiles

ClC1=C(C(C2=C(C3=NC(C4=NC=C(N=C4)C)=C5C(N([C@@H]6[C@@H]7NC[C@H]6C7)C([C@H](N8C(COCC8)=O)C)=C5)=C3C=C2CCC#N)F)=CC=C1)C

Molecular Formula

C37H35ClFN7O2

Molecular Weight

664.17

References & Citations

[1]Ye Q, et al. Discovery of INCB159020, an Orally Bioavailable KRAS G12D Inhibitor. J Med Chem. 2025 Jan 8.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Alternative Products

Catalog	Name
T204240-01	INCB159020