Products for Research Use Only

INCB159020

CAT: 0013-GTR19250427-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19250427-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
INCB159020 is a potent and orally bioavailable small molecule inhibitor selectively targeting the KRAS G12D mutant, with a binding affinity (SPR) of 2.2 nM. It has demonstrated anti-tumor efficacy in preclinical in vitro and in vivo studies, supporting its use in oncology research focused on RAS-driven cancers.
CAS Number
2923669-20-7
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
[C@@H] (C) (C=1N (C2=C (C (=NC=3C2=CC (CCC#N) =C (C3F) C4=C (C) C (Cl) =CC=C4) C=5C=NC (C) =CN5) C1) [C@H]6[C@@]7 (C[C@]6 (NC7) [H]) [H]) N8C (=O) COCC8
Molecular Formula
C37H35ClFN7O2
Molecular Weight
664.171
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products