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PEG (2000) -C-DMG

CAT: 0804-HY-168399-04Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-168399-04Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PEG (2000) -C-DMG is a PEGylated derivative of 1,2-Dimyristoyl-sn-glycerol. PEG (2000) -C-DMG can be used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of siRNA[1].
CAS Number
1443687-74-8
UNSPSC
12352211
Target
Liposome
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCCCCCCCCCCCCC(OC(COC(NCCCOCCOC)=O)COC(CCCCCCCCCCCCC)=O)=O.[n]
Molecular Weight
2600 (Approximately)
References & Citations
[1]Hobo W, , et al. Improving dendritic cell vaccine immunogenicity by silencing PD-1 ligands using siRNA-lipid nanoparticles combined with antigen mRNA electroporation. Cancer Immunol Immunother. 2013 Feb;62 (2) :285-97.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported

Chemical Information

Peg(2000)-C-dmg
CAS Number1443687-74-8
PubChem CID166638297
IUPAC Name[(2R)-3-[3-(2-methoxyethoxy)propylcarbamoyloxy]-2-tetradecanoyloxypropyl] tetradecanoate
Molecular FormulaC38H73NO8
Molecular Weight672.0
XLogP12.3
Topological Polar Surface Area109
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count39
Heavy Atom Count47
Formal Charge0
Complexity705
SMILES
CCCCCCCCCCCCCC(=O)OC[C@H](COC(=O)NCCCOCCOC)OC(=O)CCCCCCCCCCCCC
InChI
InChI=1S/C38H73NO8/c1-4-6-8-10-12-14-16-18-20-22-24-27-36(40)45-33-35(34-46-38(42)39-29-26-30-44-32-31-43-3)47-37(41)28-25-23-21-19-17-15-13-11-9-7-5-2/h35H,4-34H2,1-3H3,(H,39,42)/t35-/m1/s1
InChIKey
YWYMLVACUCXAEC-PGUFJCEWSA-N
Chemical Structure
2D Structure
2D structure of Peg(2000)-C-dmg
CAS: 1443687-74-8
CID: 166638297
Formula: C38H73NO8
MW: 672.0
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight672.0
XLogP312.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count39
Exact Mass671.53361829
Monoisotopic Mass671.53361829
Topological Polar Surface Area109 Ų
Heavy Atom Count47
Formal Charge0
Complexity705
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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