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Fenretinide glucuronide

CAT: 0804-HY-167638Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-167638Size:1 Each
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Description
Fenretinide glucuronide (4-HPR-O-glucuronide) is a metabolite formed from Fenretinide through glucuronidation. The formation of Fenretinide glucuronide enhances the water solubility of Fenretinide and facilitates its excretion. Fenretinide glucuronide holds potential for research in the field of cancer[1].
CAS Number
79982-82-4
Product Name Alternative
4-HPR-O-glucuronide
UNSPSC
12352005
Target
Drug Metabolite
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
OC([C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1OC2=CC=C(C=C2)NC(/C=C(C)/C=C/C=C(C)/C=C/C3=C(C)CCCC3(C)C)=O)=O
Molecular Formula
C32H41NO8
Molecular Weight
567.67
References & Citations
[1]Cooper JP, et al. Fenretinide metabolism in humans and mice: utilizing pharmacological modulation of its metabolic pathway to increase systemic exposure. Br J Pharmacol. 2011 Jul;163 (6) :1263-75.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported