ASPH-IN-1

• Description:

  ASPH-IN-1 (Compound 14c) is an orally active ASPH inhibitor. ASPH-IN-1 down-regulates MMP2 and MMP14 protein expression. ASPH-IN-1 exhibits anti-cancer activity against cholangiocarcinoma[1].

• UNSPSC:

  12352005

• Target:

  MMP

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cancer

• Smiles:

  O=C(OC)C1=CC=C(C=C1)C2OC(N)=C(OS(=O)(=O)CC=3C=CC=CC3)C2=O

• Molecular Formula:

  C19H17NO7S

• Molecular Weight:

  403.41

• References & Citations:

  [1]Jack R. Wands, et al. Targeting aspartate beta-hydroxylase suppresses tumor malignancy and metastasis. US20210052561A1. United States. 2020-08-24.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  MMP-14; MMP-2

• CAS Number:

  [2477878-52-5]