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4-Di-1-ASP

CAT: 0804-HY-W094758ASize: 200 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W094758ASize:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
4-Di-1-ASP is a styryl dye used to stain glioma cells in living brain tissue for analysis of cell structure, viability, proliferation and endocytosis, cytokinesis and phagocytosis, as well as for observation of mitochondrial structures in living cells. 4-Di-1-ASP fluoresces green when imaged microscopically (λex /λem = 475/606 nm) [1][2].
CAS Number
959-81-9
UNSPSC
12171500
Hazard Statement
H315, H319, H335
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/4-di-1-asp.html
Purity
99.95
Solubility
DMSO : 43.75 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C[N+]1=CC=C(/C=C/C2=CC=C(N(C)C)C=C2)C=C1.[I-]
Molecular Formula
C16H19IN2
Molecular Weight
366.24
Precautions
H315, H319, H335
References & Citations
[1]Lilia Y Kucheryavykh, et al. Visualization of implanted GL261 glioma cells in living mouse brain slices using fluorescent 4- (4- (dimethylamino) -styryl) -N-methylpyridinium iodide (ASP+) . Biotechniques. 2012 Nov;53 (5) :305-9.|[2]Jensen J H Wong, et al. Simultaneous High-Throughput Conformational and Colloidal Stability Screening Using a Fluorescent Molecular Rotor Dye, 4- (4- (Dimethylamino) styryl) -N-Methylpyridinium Iodide (DASPMI) . J Biomol Screen. 2016 Sep;21 (8) :842-50.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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