20-Hydroxyvitamin D3

• Description :

  20-Hydroxyvitamin D3 (20 (OH) D3) is a hydroxy metabolite of vitamin D3. 20-Hydroxyvitamin D3 functions as a ligand for vitamin D receptor (VDR), aryl hydrocarbon receptor (AhR), liver X receptor (LXR), and retinoic acid-related orphan receptor (ROR) . 20-Hydroxyvitamin D3 inhibits cell proliferation, induces differentiation. 20-Hydroxyvitamin D3 can be used for inflammatory and autoimmune diseases study[1].

• Product Name Alternative :

  20 (OH) D3; 20S-Hydroxyvitamin D3

• UNSPSC :

  12352211

• Target :

  Aryl Hydrocarbon Receptor; LXR; ROR; VD/VDR

• Related Pathways :

  Immunology/Inflammation; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Metabolic Disease; Inflammation/Immunology

• Purity :

  98.0

• Smiles :

  C=C1CC[C@H](O)C/C1=C/C=C2[C@@](CC[C@]3([H])[C@@](C)(O)CCCC(C)C)([H])[C@]3(C)CCC/2

• Molecular Formula :

  C27H44O2

• Molecular Weight :

  400.64

• References & Citations :

  [1]Brzeminski P, et al. Chemical synthesis, biological activities and action on nuclear receptors of 20S (OH) D3, 20S,25 (OH) 2D3, 20S,23S (OH) 2D3 and 20S,23R (OH) 2D3. Bioorg Chem. 2022 Apr;121:105660.

• Shipping Conditions :

  Dry Ice

• Storage Conditions :

  -80°C, sealed storage, away from moisture and light

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [651734-12-2]