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20-Hydroxyvitamin D3

CAT: 0804-HY-154825Size: 1 EachDry Ice: YesHazardous: No
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CAT#:0804-HY-154825Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
20-Hydroxyvitamin D3 (20 (OH) D3) is a hydroxy metabolite of vitamin D3. 20-Hydroxyvitamin D3 functions as a ligand for vitamin D receptor (VDR), aryl hydrocarbon receptor (AhR), liver X receptor (LXR), and retinoic acid-related orphan receptor (ROR) . 20-Hydroxyvitamin D3 inhibits cell proliferation, induces differentiation. 20-Hydroxyvitamin D3 can be used for inflammatory and autoimmune diseases study[1].
CAS Number
651734-12-2
Product Name Alternative
20 (OH) D3; 20S-Hydroxyvitamin D3
UNSPSC
12352211
Target
Aryl Hydrocarbon Receptor; LXR; ROR; VD/VDR
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Purity
98.0
Smiles
C=C1CC[C@H](O)C/C1=C/C=C2[C@@](CC[C@]3([H])[C@@](C)(O)CCCC(C)C)([H])[C@]3(C)CCC/2
Molecular Formula
C27H44O2
Molecular Weight
400.64
References & Citations
[1]Brzeminski P, et al. Chemical synthesis, biological activities and action on nuclear receptors of 20S (OH) D3, 20S,25 (OH) 2D3, 20S,23S (OH) 2D3 and 20S,23R (OH) 2D3. Bioorg Chem. 2022 Apr;121:105660.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C, sealed storage, away from moisture and light
Scientific Category
Natural Products
Clinical Information
No Development Reported

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