CCC-0975

CAT: 0804-HY-149158-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-149158-01Size:5 mg
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Description
CCC-0975 is a hepatitis B virus (HBV) inhibitor (EC50=10 μM) . CCC-0975 interferes with the conversion of relaxed circular DNA (rcDNA) to cccDNA, synchronously reducing cccDNA and its precursor deproteinized rcDNA (DP-rcDNA) without promoting their intracellular degradation. CCC-0975 is promising for research of chronic hepatitis B[1].
CAS Number
[432018-03-6]
UNSPSC
12352005
Target
HBV
Related Pathways
Anti-infection
Field of Research
Inflammation/Immunology
Purity
99.49
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(CN(S(=O)(C1=CC=CC=C1)=O)C2=CC(C(F)(F)F)=CC=C2Cl)NCC3=CC=NC=C3
Molecular Formula
C21H17ClF3N3O3S
Molecular Weight
483.89
References & Citations
[1]Cai D, et al. Identification of disubstituted sulfonamide compounds as specific inhibitors of hepatitis B virus covalently closed circular DNA formation. Antimicrob Agents Chemother. 2012 Aug;56 (8) :4277-88.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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