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SEP-4199

CAT: 0804-HY-14545BSize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-14545BSize:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SEP-4199 is a nonracemic 85:15 ratio of Aramisulpride (HY-109167) and Esamisulpride (HY-126068) . SEP-4199 exhibits significant differences in relative potency at two different receptors (5-HT7R and D2R) compared to the racemate. SEP-4199 exhibits antidepressant effects[1].
CAS Number
[2974362-88-2]
UNSPSC
12352005
Target
5-HT Receptor; Dopamine Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
CCN1[C@@H](CNC(C2=CC(S(=O)(CC)=O)=C(N)C=C2OC)=O)CCC1.CCN3[C@H](CNC(C4=CC(S(=O)(CC)=O)=C(N)C=C4OC)=O)CCC3
Molecular Formula
C17H27N3O4S
Molecular Weight
369.48
References & Citations
[1]Hopkins SC, et al. Discovery of Nonracemic Amisulpride to Maximize Benefit/Risk of 5-HT7 and D2 Receptor Antagonism for the Treatment of Mood Disorders. Clin Pharmacol Ther. 2021 Sep;110 (3) :808-815.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT7 Receptor; D2 Receptor

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