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(R) -Zevaquenabant

CAT: 0804-HY-141411B-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-141411B-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(R) -Zevaquenabant ((R) -MRI-1867) is the enantiomer of Zevaquenabant. Zevaquenabant ((S) -MRI-1867) is a peripherally restricted, orally bioavailable dual cannabinoid CB1 receptor and inducible NOS antagonist. Zevaquenabant ameliorates obesity-induced chronic kidney disease (CKD).
Product Name Alternative
(R) -MRI-1867
UNSPSC
12352005
Target
Cannabinoid Receptor; Drug Isomer; NO Synthase
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others
Field of Research
Others
Purity
99.15
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=S(/N=C(N1N=C(C2=CC=C(Cl)C=C2)[C@H](C3=CC=CC=C3)C1)/N=C(N)/C)(C4=CC=C(C(F)(F)F)C=C4)=O
Molecular Formula
C25H21ClF3N5O2S
Molecular Weight
547.98
References & Citations
[1]Udi S, et al. Dual inhibition of cannabinoid CB1 receptor and inducible NOS attenuates obesity-induced chronic kidney disease [published correction appears in Br J Pharmacol. 2021 Mar;178 (5) :1250]. Br J Pharmacol. 2020;177 (1) :110-127.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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