DBCO-PEG9-amine (TFA)

• Description :

  DBCO-PEG9-amine (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DBCO-PEG9-amine (TFA) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups[1].

• UNSPSC :

  12352005

• Target :

  PROTAC Linkers

• Related Pathways :

  PROTAC

• Field of Research :

  Cancer

• Purity :

  96.38

• Smiles :

  O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN)=O.O=C(O)C(F)(F)F

• Molecular Formula :

  C41H58F3N3O13

• Molecular Weight :

  857.91

• References & Citations :

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, protect from light, stored under nitrogen)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported