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BLX-3887

CAT: 0804-HY-138154-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-138154-01Size:1 mg
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Description
BLX-3887 is a selective 15-lipoxygenase type 1 (15-LO-1) inhibitor with an IC50 of 32 nM. BLX-3887 can be utilized in research related to the 15-LO pathways[1].
CAS Number
934758-70-0
UNSPSC
12352005
Target
Lipoxygenase
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Smiles
O=C(C1=NNC(Cl)=C1Cl)NC2=CC=C(F)C=C2Cl
Molecular Formula
C10H5Cl3FN3O
Molecular Weight
308.52
References & Citations
[1]Archambault AS, et al. Comparison of eight 15-lipoxygenase (LO) inhibitors on the biosynthesis of 15-LO metabolites by human neutrophils and eosinophils. PLoS One. 2018 Aug 17;13 (8) :e0202424.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
15-LOX