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Deacetylforskolin

CAT: 0804-HY-137934-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-137934-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Deacetylforskolin is a deacetylated derivative of forskolin that can be extracted from C. forskohlii. Deacetylforskolin activates rat adipocyte adenylyl cyclase (IC50 = 20 µM), inhibits glucose transport in rat adipocyte plasma membranes and exhibits antihypertensive activity[1][2].
CAS Number
64657-20-1
Product Name Alternative
7-Deacetylforskolin
UNSPSC
12352211
Hazard Statement
H312
Target
Endogenous Metabolite
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Smiles
O[C@@]([C@@]([C@H]1O)(O[C@@]2(C)C=C)C)(C(C2)=O)[C@]([C@@](C3(C)C)([H])[C@@H]1O)([C@H](CC3)O)C
Molecular Formula
C20H32O6
Molecular Weight
368.46
Precautions
P280-P302+P352-P362+P364-P501
References & Citations
[1]Joost HG, et al. Activation of adenylate cyclase and inhibition of glucose transport in rat adipocytes by forskolin analogues: structural determinants for distinct sites of action. Mol Pharmacol. 1988 Apr;33 (4) :449-53.|[2]Bhat SV, et al. The antihypertensive and positive inotropic diterpene forskolin: effects of structural modifications on its activity. J Med Chem. 1983 Apr;26 (4) :486-92.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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