Products for Research Use Only
RegisterLogin

Sp-TTPαS (tetrasodium)

CAT: 0804-HY-137613ASize: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-137613ASize:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Sp-TTPαS tetrasodium is a competitivesterile alpha motif and HD domain containing protein 1 (SAMHD1) hydrolysis inhibitor. Sp-TTPαS tetrasodium competitively inhibits SAMHD1 triphosphohydrolase activity with a Ki value of 46 µM[1].
UNSPSC
12352005
Target
HIV
Related Pathways
Anti-infection
Field of Research
Infection; Inflammation/Immunology
Smiles
O[C@H]1C[C@H](N2C(NC(C(C)=C2)=O)=O)O[C@@H]1CO[P@@](OP(OP(O[Na])(O[Na])=O)(O[Na])=O)(S[Na])=O
Molecular Formula
C10H13N2Na4O13P3S
Molecular Weight
586.16
References & Citations
[1]Morris ER, et al. Probing the Catalytic Mechanism and Inhibition of SAMHD1 Using the Differential Properties of Rp- and Sp-dNTPαS Diastereomers. Biochemistry. 2021 Jun 1;60 (21) :1682-1698.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-137613CRp-TTPαS (tetrasodium)
HY-137613Sp-TTPαS
HY-137614ASp-GTPαS (tetrasodium)
HY-137619ASp-dCTPαS (tetrasodium)
HY-137616ASp-dUTPαS (tetrasodium)
HY-137626ASp-ATPαS (tetrasodium)
HY-137612ASp-UTP-α-S (tetrasodium)
HY-137618ASp-dGTPαS (tetrasodium)
HY-137651ASp-2'-F-dATP-αS (tetrasodium)
HY-137648ASp-2'-O-Me-GTPαS (tetrasodium)

Alternative Products

CatalogName
GTR19263901-01Sp-TTPαS tetrasodium
T212252-01Rp-TTPαS tetrasodium
T212148-01Sp-dGTPαS tetrasodium
GTR19273158-01Sp-dCTPαS tetrasodium
TSW-01151-01Sp-dUTPαS tetrasodium
GTR19273954-01Sp-UTP-α-S tetrasodium
GTR19273926-01Sp-GTPαS tetrasodium
GTR19273900-01Sp-2'-F-dATP-αS tetrasodium
GTR19279953-01Sp-2'-O-Me-CTPαS tetrasodium
GTR19279772-01Sp-2'-O-Me-GTPαS tetrasodium

Popular Products