Anhydro abiraterone

• Description :

  Anhydro abiraterone is a degradation product of Abiraterone acetate (HY-75054) . Abiraterone acetate (CB7630) is an oral, potent, selective, and irreversible inhibitor of CYP17A1 with antiandrogen activity[1][2].

• CAS Number :

  [154229-20-6]

• UNSPSC :

  12352005

• Hazard Statement :

  H361-H373-H410

• Target :

  Drug Metabolite

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Cancer

• Smiles :

  C[C@@]1(C(C2=CN=CC=C2)=CC3)[C@]3([H])[C@@](CC=C4[C@@]5(CCC=C4)C)([H])[C@]5([H])CC1

• Molecular Formula :

  C24H29N

• Molecular Weight :

  331.49

• Precautions :

  P260-P273-P280-P391-P405-P501

• References & Citations :

  [1]Deepak Krishna Mhaske, et al. The first RP-UHPLC method for simultaneous quantification of abiraterone acetate, its four degradants, and six specified process impurities and correct identification of all analytes based on molecular weight. J Pharm Biomed Anal. 2023 Sep 20:234:115568. |[2]Stein MN, et al. Androgen synthesis inhibitors in the treatment of castration-resistant prostate cancer. Asian J Androl. 2014 May-Jun;16 (3) :387-400.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound2

• Clinical Information :

  No Development Reported