Leucinostatin H

• Description :

  Leucinostatin H is a polypeptide antibiotic discovered in Paecilomyces marquandii, characterized by a tertiary amine-oxide terminal group. Leucinostatin H exhibits inhibitory activity against Gram-positive bacteria, such as Bacillus subtilis, B. cereus, and Staphylococcus aureus (MIC 10-100 μg/mL) . Leucinostatin H holds potential for research in anti-infective and plant disease control applications[1].

• CAS Number :

  [109539-58-4]

• UNSPSC :

  12352005

• Target :

  Antibiotic; Bacterial

• Related Pathways :

  Anti-infection

• Field of Research :

  Infection

• Smiles :

  O=C(N[C@H](C[N+](C)(C)[O-])C)CCNC(C(C)(C)NC(C(C)(C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC(C(C)(C)NC([C@H]([C@H](O)C(C)C)NC([C@H](CC(C)C)NC([C@@H]1C[C@@H](CN1C(/C=C/[C@@H](C)CC)=O)C)=O)=O)=O)=O)=O)=O)=O)=O

• Molecular Formula :

  C57H103N11O12

• Molecular Weight :

  1134.49

• References & Citations :

  [1]Radics L, et al. Leucinostatins H and K, two novel peptide antibiotics with tertiary amine-oxide terminal group from Paecilomyces marquandii isolation, structure and biological activity. J Antibiot (Tokyo) . 1987 May;40 (5) :714-6.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported