YJC-10592

CAT: 0804-HY-136768Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-136768Size:1 Each

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Description

YJC-10592 is an orally active CCR-2 antagonist. YJC-10592 binds to HAS. YJC-10592 can be used in the research of asthma and idiopathic dermatitis[1].

CAS Number

1226894-87-6

UNSPSC

12352005

Target

CCR

Related Pathways

GPCR/G Protein; Immunology/Inflammation

Field of Research

Inflammation/Immunology

Smiles

O=C(NCC(N[C@H]1CN(CCN2CCN(C(C3=CC=CC=C3Cl)=O)CC2)CC1)=O)C4=CC=CC(C(F)(F)F)=C4

Molecular Formula

C27H31ClF3N5O3

Molecular Weight

566.01

References & Citations

[1]Du ES, et al. Pharmacokinetics of YJC-10592, a novel chemokine receptor 2 (CCR-2) antagonist, in rats. Arch Pharm Res. 2016 Jun;39 (6) :833-42.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CCR2

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