Belotecan (Standard)

• Description :

  Belotecan (Standard) is the analytical standard of Belotecan. This product is intended for research and analytical applications. Belotecan (CKD-602 free base) is a DNA topoisomerase I inhibitor. Belotecan induces cell apoptosis and cell-cycle arrest. Belotecan is a camptothecin analogue with anti-tumor effects, it can be used for the research of cancer[1].

• CAS Number :

  [256411-32-2]

• UNSPSC :

  12352100

• Target :

  Apoptosis; Reference Standards; Topoisomerase

• Related Pathways :

  Apoptosis; Cell Cycle/DNA Damage; Others

• Field of Research :

  Cancer

• Smiles :

  O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C(CCNC(C)C)C5=CC=CC=C5N=C4C3=C2)=O

• Molecular Formula :

  C25H27N3O4

• Molecular Weight :

  433.50

• References & Citations :

  [1]Lee S, et al. CKD-602, a topoisomerase I inhibitor, induces apoptosis and cell-cycle arrest and inhibits invasion in cervical cancer. Mol Med. 2019 May 28;25 (1) :23.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference Standards