I-AZD1775 (TFA)

CAT: 0804-HY-133703ASize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-133703ASize:1 Each
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Description
I-AZD1775 (TFA) is an immobilizable analogue of AZD1775. i-AZD1775 (TFA) retains the ability to inhibit WEE1 in vitro. i-AZD1775 (TFA) can be studied in anticancer research[1].
CAS Number
[2858813-30-4]
UNSPSC
12352005
Target
Wee1
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=C(C(F)(F)F)O.O=C1C2=CN=C(NC3=CC=C(N4CCN(CCCN)CC4)C=C3)N=C2N(N1CC=C)C5=CC=CC(C(C)(C)O)=N5
Molecular Formula
C31H38F3N9O4
Molecular Weight
657.69
References & Citations
[1]Wright, G., et al., (2017) . Dual Targeting of WEE1 and PLK1 by AZD1775 Elicits Single Agent Cellular Anticancer Activity. ACS chemical biology, 12 (7), 1883–1892.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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