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Ezetimibe ketone (Standard)

CAT: 0804-HY-133114R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-133114R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
191330-56-0
UNSPSC
12352005
Target
Autophagy; Keap1-Nrf2
Related Pathways
Autophagy; NF-κB
Field of Research
Cancer; Cardiovascular Disease
Smiles
O=C1N(C2=CC=C(F)C=C2)[C@H](C3=CC=C(O)C=C3)[C@H]1CCC(C4=CC=C(F)C=C4)=O
Molecular Formula
C24H19F2NO3
Molecular Weight
407.41
References & Citations
[1]Yijun Zhu, et al. Efficient and scalable process for the synthesis of antihypercholesterolemic drug ezetimibe. Synthetic Communications. 2016, 46:20, 1687-1693.|[2]Lee DH, et al. Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis. Free Radic Biol Med. 2016 Sep 12;99:520-532.|[3]Chang E, et al. Ezetimibe improves hepatic steatosis in relation to autophagy in obese and diabetic rats. World J Gastroenterol. 2015 Jul 7;21 (25) :7754-63.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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